Orf-I and Orf-II-Encoded Proteins in HTLV-1 Infection and Persistence
نویسندگان
چکیده
منابع مشابه
Orf-I and Orf-II-Encoded Proteins in HTLV-1 Infection and Persistence
The 3' end of the human T-cell leukemia/lymphoma virus type-1 (HTLV-1) genome contains four overlapping open reading frames (ORF) that encode regulatory proteins. Here, we review current knowledge of HTLV-1 orf-I and orf-II protein products. Singly spliced mRNA from orf-I encodes p12, which can be proteolytically cleaved to generate p8, while differential splicing of mRNA from orf-II results in...
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DURING the spring and early summer of 1955 an unusually large number of cases of orf were seen in patients attending the various skin clinics in Northern Ireland. The condition aroused considerable interest, and it is hoped that these notes may prove helpful to local practitioners. Orf is an infective disease, caused by a filtrable virus of the pox group, affecting commonly sheep and goats. The...
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independent replicate experiments. Deletion of these genes affects the fitness of mutant strains in iron deficiency. The requirement for growth of each gene was quantified as a log 2 ratio of growth of the corresponding mutant strain in YPD with BPS compared to YPD alone. The log 2 fitness represents the average of the significant values in these experiments. A negative value indicates sensitiv...
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ژورنال
عنوان ژورنال: Viruses
سال: 2011
ISSN: 1999-4915
DOI: 10.3390/v3060861